Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 2, Issue 1 , Pages 36-42 , January 2006

Positron emission tomography and magnetic resonance imaging in the diagnosis and prediction of dementia

  • William Jagust

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: 510-643-6537; Fax: 510-642-3192

References 

  1. Knopman DS , DeKosky ST , Cummings JL , Chui H , Corey-Bloom J , Relkin N , et al.   Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology . Neurology . 2001;56:1143–1153
  2. Hirata Y , Matsuda H , Nemoto K , Ohnishi T , Hirao K , Yamashita F , et al.   Voxel-based morphometry to discriminate early Alzheimer’s disease from controls . Neurosci Lett . 2005;382:269–274
  3. Scheltens P , Leys D , Barkhof F , Huglo D , Weinstein HC , Vermersch P , et al.   Atrophy of medial temporal lobes on MRI in “probable” Alzheimer’s disease and normal ageing (Diagnostic value and neuropsychological correlates) . J Neurol Neurosurg Psychiatr . 1992;55:967–972
  4. Laakso MP , Soininen H , Partanen K , Lehtovirta M , Hallikainen M , Hänninen T , et al.   MRI of the hippocampus in Alzheimer’s disease (Sensitivity, specificity, and analysis of the incorrectly classified subjects) . Neurobiol Aging . 1998;19:23–31
  5. Laakso MP , Partanen K , Riekkinen P , Lehtovirta M , Helkala E-L , Hallikainen M , et al.   Hippocampal volumes in Alzheimer’s disease, Parkinson’s disease with and without dementia, and in vascular dementia (an MRI study) . Neurology . 1996;46:678–681
  6. Frisoni GB , Laakso MP , Beltramello A , Geroldi C , Bianchetti A , Soininen H , et al.   Hippocampal and entorhinal cortex atrophy in frontotemporal dementia and Alzheimer’s disease . Neurology . 1999;52:91–100
  7. Nagy Z , Hindley NJ , Braak H , Braak E , Yilmazer-Hanke DM , Schultz C , et al.   Relationship between clinical and radiological diagnostic criteria for Alzheimer’s disease and the extent of neuropathology as reflected by ‘stages’ (a prospective study) . Dement Geriatr Cogn Disord . 1999;10:109–114
  8. Gosche KM , Mortimer JA , Smith CD , Markesbery WR , Snowdon DA . Hippocampal volume as an index of Alzheimer neuropathology (findings from the Nun Study) . Neurology . 2002;58:1476–1482
  9. Jack CR , Dickson DW , Parisi JE , Xu YC , Cha RH , O’Brien PC , et al.   Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia . Neurology . 2002;58:750–757
  10. Fotenos AF , Snyder AZ , Girton LE , Morris JC , Buckner RL . Normative estimates of cross-sectional and longitudinal brain volume decline in aging and AD . Neurology . 2005;64:1032–1039
  11. Fox NC , Freeborough PA , Rossor MN . Visualization and quantification of rates of atrophy in Alzheimer’s disease . Lancet . 1996;348:94–97
  12. Fox NC , Warrington EK , Rossor MN . Serial magnetic resonance imaging of cerebral atrophy in preclinical Alzheimer’s disease . Lancet . 1999;353:2125
  13. Silbert LC , Quinn JF , Moore MM , Corbridge E , Ball MJ , Murdoch G , et al.   Changes in premorbid brain volume predict Alzheimer’s disease pathology . Neurology . 2003;61:487–492
  14. Jack CR , Petersen RC , Xu YC , O’Brien PC , Smith GE , Ivnik RJ , et al.   Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment . Neurology . 1999;52:1397–1403
  15. Visser PJ , Verhey FR , Hofman PA , Scheltens P , Jolles J . Medial temporal lobe atrophy predicts Alzheimer’s disease in patients with minor cognitive impairment . J Neurol Neurosurg Psychiatry . 2002;72:491–497
  16. Jack CR , Shiung MM , Gunter JL , O’Brien PC , Weigand SD , Knopman DS , et al.   Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD . Neurology . 2004;62:591–600
  17. Jack CR , Shiung MM , Weigand SD , O’Brien PC , Gunter JL , Boeve BF , et al.   Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI . Neurology . 2005;65:1227–1231
  18. deToledo-Morrell L , Stoub TR , Bulgakova M , Wilson RS , Bennett DA , Leurgans S , et al.   MRI-derived entorhinal volume is a good predictor of conversion from MCI to AD . Neurobiol Aging . 2004;25:1197–1203
  19. DeCarli C , Mungas D , Harvey D , Reed B , Weiner M , Chui H , et al.   Memory impairment, but not cerebrovascular disease, predicts progression of MCI to dementia . Neurology . 2004;63:220–227
  20. Minoshima S , Frey KA , Koeppe RA , Foster NL , Kuhl DE . A diagnostic approach in Alzheimer’s disease using three-dimensional stereotactic surface projections of fluorine-18-FDG PET . J Nucl Med . 1995;36:1238–1248
  21. Minoshima S , Giordani B , Berent S , Frey KA , Foster NL , Kuhl DE . Metabolic reduction in the posterior cingulate cortex in very early Alzheimer’s disease . Ann Neurol . 1997;42:85–94
  22. Herholz K . PET studies in dementia . Ann Nucl Med . 2003;17:79–89
  23. Holmes C , Cairns N , Lantos P , Mann A . Validity of current clinical criteria for Alzheimer’s disease, vascular dementia and dementia with Lewy bodies . Br J Psychiatry . 1999;174:45–50
  24. Lim A , Tsuang D , Kukull W , Nochlin D , Leverenz J , McCormick W , et al.   Clinico-neuropathological correlation of Alzheimer’s disease in a community-based case series . J Am Geriatr Soc . 1999;47:564–569
  25. Hoffman JM , Welsh-Bohmer KA , Hanson M , Crain B , Hulette C , Earl N , et al.   FDG PET imaging in patients with pathologically verified dementia . J Nucl Med . 2000;41:1920–1928
  26. Silverman DH , Small GW , Chang CY , Lu CS , Kung De Aburto MA , Chen W , et al.   Positron emission tomography in evaluation of dementia (Regional brain metabolism and long-term outcome) . JAMA . 2001;286:2120–2127
  27. Jagust W , Thisted R , Devous MD , Van Heertum R , Mayberg H , Jobst K , et al.   SPECT perfusion imaging in the diagnosis of Alzheimer’s disease (A clinical-pathologic study) . Neurology . 2001;56:950–956
  28. Albin RL , Minoshima S , D’Amato CJ , Frey KA , Kuhl DA , Sima AAF . Fluoro-deoxyglucose positron emission tomography in diffuse Lewy body disease . Neurolgy . 1996;47:462–466
  29. Imamura T , Ishii K , Sasaki M , Kitagaki H , Yamaji S , Hirono N , et al.   Regional cerebral glucose metabolism in dementia with Lewy bodies and Alzheimer’s disease (A comparative study using positron emission tomography) . Neurosci Lett . 1997;235:49–52
  30. Minoshima S , Foster NL , Sima AA , Frey KA , Albin RL , Kuhl DE . Alzheimer’s disease versus dementia with Lewy bodies (cerebral metabolic distinction with autopsy confirmation) . Ann Neurol . 2001;50:358–365
  31. Ishii K , Sakamoto S , Sasaki M , Kitagaki H , Yamaji S , Hashimoto M , et al.   Cerebral glucose metabolism in patients with frontotemporal dementia . J Nucl Med . 1998;39:1875–1878
  32. Santens P , De Bleecker J , Goethals P , Strijckmans K , Lemahieu I , Slegers G , et al.   Differential regional cerebral uptake of (18)F-fluoro-2-deoxy-D-glucose in Alzheimer’s disease and frontotemporal dementia at initial diagnosis . Eur Neurol . 2001;45:19–27
  33. Reiman EM , Caselli RJ , Yun LS , Chen K , Bandy D , Minoshima S , et al.   Preclinical evidence of Alzheimer’s disease in persons homozygous for the e4 allele for apolipoprotein E . N Engl J Med . 1996;334:752–758
  34. Reiman EM , Chen K , Alexander GE , Caselli RJ , Bandy D , Osborne D , et al.   Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer’s dementia . Proc Natl Acad Sci U S A . 2004;101:284–289
  35. Kennedy AM , Frackowiak RSJ , Newman SK , Bloomfield PM , Seaward J , Roques P , et al.   Deficits in cerebral glucose metabolism demonstrated by positron emission tomography in individuals at risk of familial Alzheimer’s disease . Neurosci Lett . 1995;186:17–20
  36. Arnaiz E , Jelic V , Almkvist O , Wahlund LO , Winblad B , Valind S , et al.   Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment . Neuroreport . 2001;12:851–855
  37. Chetelat G , Desgranges B , De La Sayette V , Viader F , Eustache F , Baron JC . Mild cognitive impairment (Can FDG-PET predict who is to rapidly convert to Alzheimer’s disease?) . Neurology . 2003;60:1374–1377
  38. de Leon MJ , Convit A , Wolf OT , Tarshish CY , DeSanti S , Rusinek H , et al.   Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET) . Proc Natl Acad Sci U S A . 2001;98:10966–10971
  39. Dickerson BC , Salat DH , Bates JF , Atiya M , Killiany RJ , Greve DN , et al.   Medial temporal lobe function and structure in mild cognitive impairment . Ann Neurol . 2004;56:27–35
  40. Small SA , Perera GM , DeLaPaz R , Mayeux R , Stern Y . Differential regional dysfunction of the hippocampal formation among elderly with memory decline and Alzheimer’s disease . Ann Neurol . 1999;45:466–472
  41. Smith CD , Andersen AH , Kryscio RJ , Schmitt FA , Kindy MS , Blonder LX , et al.   Altered brain activation in cognitively intact individuals at high risk for Alzheimer’s disease . Neurology . 1999;53:1391–1396
  42. Shoghi-Jadid K , Small GW , Agdeppa ED , Kepe V , Ercoli LM , Siddarth P , et al.   Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease . Am J Geriatr Psychiatry . 2002;10:24–35
  43. Klunk WE , Engler H , Nordberg A , Wang Y , Blomqvist G , Holt DP , et al.   Imaging brain amyloid in Alzheimer’s disease with Pittsburgh Compound-B . Ann Neurol . 2004;55:306–319
  44. Verhoeff NP , Wilson AA , Takeshita S , Trop L , Hussey D , Singh K , et al.   In-vivo imaging of Alzheimer disease beta-amyloid with [11C]SB-13 PET . Am J Geriatr Psychiatry . 2004;12:584–595
  45. Davis DG , Schmitt FA , Wekstein DR , Markesbery WR . Alzheimer neuropathologic alterations in aged cognitively normal subjects . J Neuropathol Exp Neurol . 1999;58:376–388
  46. Mueller SG , Weiner MW , Thal LJ , Petersen RC , Jack CJ , Jagust W . Ways toward an early diagnosis in Alzheimer’s disease (The Alzheimer’s Disease Neuroimaging Initiative) . Alzheimer’s and Dementia . 2005;1:55–66

PII: S1552-5260(05)00501-7

doi: 10.1016/j.jalz.2005.11.002

Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 2, Issue 1 , Pages 36-42 , January 2006

Article Tools

* Image Usage & Resolution