Contents

Article Outline

• Editorial
• Featured Article
• Review Articles
• Short Report
• Association Pages

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Editorial 

1 When will dementia become a curable disease and Alzheimer’s a forgotten word?

Zaven S. Khachaturian

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Featured Article 

2 Comparison of clinical and neuropathologic diagnoses of Alzheimer’s disease in 3 epidemiologic samples

Brenda L. Plassman, Ara S. Khachaturian, Jeannette J. Townsend, Melvyn J. Ball, David C. Steffens, Carol E. Leslie, JoAnn T. Tschanz, Maria C. Norton, James R. Burke, Kathleen A. Welsh-Bohmer, Christine M. Hulette, Randal R. Nixon, Mary Tyrey, and John C.S. Breitner

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Review Articles 

12 The NIH Cognitive and Emotional Health Project . Report of the Critical Evaluation Study Committee

Hugh C. Hendrie, Marilyn S. Albert, Meryl A. Butters, Sujuan Gao, David S. Knopman, Lenore J. Launer, Kristine Yaffe, Bruce N. Cuthbert, Emmeline Edwards, and Molly V. Wagster

33 Commentary on “The NIH Cognitive and Emotional Health Project. Report of the Critical Evaluation Study Committee”

Lewis H. Kuller

36 Positron emission tomography and magnetic resonance imaging in the diagnosis and prediction of dementia

William Jagust

43 Synaptic targeting by Aβ oligomers (ADDLS) as a basis for memory loss in early Alzheimer’s disease

William L. Klein

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Short Report 

56 The Northern Ireland life review/life storybook project for people with dementia

Barbara K. Haight, Faith Gibson, and Yvonne Michel

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Association Pages 

9A Alzheimer’s Association Update

11A Peer Review: A Pillar of the Alzheimer’s Association Research Grants Program