62 The Nevada Vital Aging Initiative: A private-public partnership to study early predictors of dementia
Leon Thal, Lewis Kuller, Keith Bowman, John Breitner, Denis Evans, Lindsey Farrer, Richard Frank, Ara S. Khachaturian, Zaven S. Khachaturian, Walter Kukull, Javier Nieto, Ronald Petersen, Mark Sager, Paul Scherr, and Lisa J. Bain, reporter
Association Pages
68 Alzheimer’s Association Update
Cover image courtesy of Drs. William Jagust and Ansgar Furst, University of California, Berkeley and Lawrence Berkeley National Laboratory.
The top pair of images is a patient with frontotemporal lobar degeneration (FTLD), the center pair is a patient with Alzheimer’s disease (AD), and the bottom pair is a normal older adult. Images on the left column are FDG-PET superimposed on the MRI. Images on the right column are PET with Pittsburgh compound B (PIB) superimposed on the MRI. Left column images show frontal hypometabolism in FTLD patient, parietal hypometabolism in AD patient, and normal metabolism in the normal older adult. Right column images show PIB binding only in the AD patient and not the FTLD patient or normal adult.