Mild cognitive impairment and cognitive impairment, no dementia: Part A, concept and diagnosis

Chertkow, Howard; Nasreddine, Ziad; Joanette, Yves; Drolet, Valérie; Kirk, John; Massoud, Fadi; Belleville, Sylvie; Bergman, Howard

doi:10.1016/j.jalz.2007.07.013

« Previous Next »Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 3, Issue 4 , Pages 266-282, October 2007

Mild cognitive impairment and cognitive impairment, no dementia: Part A, concept and diagnosis

Howard Chertkow
- Bloomfield Centre for Research in Aging, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada
- Division of Geriatric Medicine, Department of Medicine, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada
- Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
- Centre de recherche, Institut Universitaire de Gériatrie de Montréal, Montreal, Quebec, Canada
- Corresponding author. Tel.: (514) 340-8260; Fax: (514) 340-8295.
Ziad Nasreddine
- Département de médecine, service de neurologie, Hôpital Charles LeMoyne and Université de Sherbrooke, Montreal, Quebec, Canada
Yves Joanette
- Centre de recherche, Institut Universitaire de Gériatrie de Montréal, Montreal, Quebec, Canada
- Faculté de Médicine, Université de Montréal, Montréal, Quebec, Canada
Valérie Drolet
- Centre de recherche, Institut Universitaire de Gériatrie de Montréal, Montreal, Quebec, Canada
John Kirk
- Division of Geriatric Medicine, Department of Medicine, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada
Fadi Massoud
- Service de Gériatrie, Centre Hospitalier de l’Université de Montréal, and Département de Médecine, Université de Montréal, Montréal, Quebec, Canada
Sylvie Belleville
- Centre de recherche, Institut Universitaire de Gériatrie de Montréal, Montreal, Quebec, Canada
- Department de Psychologie, Université de Montréal, Montréal, Quebec, Canada
Howard Bergman
- Bloomfield Centre for Research in Aging, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada
- Division of Geriatric Medicine, Department of Medicine, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada

Abstract

Mild cognitive impairment (MCI) and cognitive impairment, no dementia (CIND) are controversial emerging terms that encompass the clinical state between elderly normal cognition and dementia. This article reviews recent work on the classification of MCI and CIND, their prognosis, and diagnostic approaches and presents evidence-based recommendations approved at the meeting of the Third Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD3) held in Montreal in March, 2006. New short tools such as the Montreal Cognitive Assessment are making it easier for family physicians to confidently attach the label of MCI.

Keywords: Mild cognitive impairment, Alzheimer’s disease, Dementia, Diagnosis, Cognitive impairment, no dementia