« Previous
Next »
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 4, Issue 4
, Pages 233-238
, July 2008
Perspective on race and ethnicity in Alzheimer's disease research
References
- . Race and ethnicity in the genome era: the complexity of the constructs. Am Psychologist. 2005;60:9–15
- Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiologic research. Am J Public Health. 2005;95:2161–2168
- . The dispersion of modern humans. In: Jones S, Matrtin R, Philbeam D editor. The Cambridge encyclopedia of human evolution. New York: Cambridge University Press; 1992;p. 389–402
- . Statistical abstract of the United States. 114th ed.. Washington, DC: U.S. Government Printing Office; 1994;4
- . Cultural diversity and Alzheimer disease: introduction. Alzheimer Dis Assoc Disord. 2002;16(Suppl. 2):S41–S42
- Complete ascertainment of dementia in the Swedish Twin Registry: the HARMONY Study. Neurobiol Aging. 2005;26:439–447
- . Categorization of humans in biomedical research: genes, race and disease. http//genomebiology.com/2002/3/7comment/2007
- . The cultural influence of values, norms, meanings, and perceptions in understanding dementia in ethnic minorities. Alzheimer Dis Assoc Disord. 2002;16(Suppl. 2):S56–S63
- . Research agenda for understanding Alzheimer disease in diverse populations: Work Group on Cultural Diversity, Alzheimer's Association. Alzheimer Dis Assoc Disord. 2002;16(Suppl. 2):S96–S100
- Apolipoprotein E polymorphism and Alzheimer disease: the India-US Cross-National Dementia Study. Arch Neurol. 2000;57:824–830
- . Lessons learned from international comparative crosscultural studies on dementia. Am J Geriatr Psychiatry. 2006;14:480–488
- . About a peculiar disease of the cerebral cortex. Alzheimer Disease Assoc Disord. 1987;1:3–8[originally published in 1907]
- . Individual estimates of European genetic admixture associated with lower body-mass index, plasma glucose, and prevalence of type II diabetes in Pima Indians. Am J Hum Genet. 2000;66:527–538
- . Unequal by nature: a geneticist's perspective on human differences. Daedalus. 2002;131:81–88
- . Familial Alzheimer's disease in American descendants of the Volga Germans: probable genetic founder effect. Ann Neurol. 1988;23:25–31
- Apolipoprotein E and Alzheimer's disease: ethnic variation in genotypic risks. Ann Neurol. 1995;37:254–259
- Pathways: a culturally appropriate obesity-prevention program for American Indian schoolchildren. Am J Clin Nutr. 1999;69:796–802
- Belmont Report (Ethical principles and guidelines for the protection of human subjects of research). Washington, DC: U.S. Government Printing Office; 1978;
- . Influence of education and occupation on the incidence of Alzheimer's disease. JAMA. 1994;271:1004–1010
- Incidence of Alzheimer disease in African Americans, Caribbean Hispanics, and Caucasians in northern Manhattan. Neurology. 2001;56:49–56
- Prevalence of Alzheimer's disease and dementia in two communities: Nigerian Africans and African Americans. Am J Psychiatry. 1995;152:1485–1492
- Incidence and prevalence of dementia in the Cardiovascular Health Study. J Am Geriatr Soc. 2004;52:195–204
- . Progression of Alzheimer's disease in black and white patients: the CERAD experience, part XVI. Consortium to Establish a Registry for Alzheimer's Disease. Neurology. 1998;51:15–18
- Racial differences in the progression of cognitive decline in Alzheimer disease. Am J Geriatr Psychiatry. 2005;13:959–967
- Incidence of Alzheimer's disease in a rural community in India: the Indo-US Study. Neurology. 2001;57:985–989
- The prevalence of dementia and Alzheimer's disease in Shanghai: impact of age, gender, and education. Ann Neurol. 1990;27:428–437
- Alzheimer's disease is rare in Cree. Int Psychogeriatr. 1993;5:5–14
- Genetic factors for the development of Alzheimer disease in the Cherokee Indian. Arch Neurol. 1996;53:997–1000
- Comparison of Alzheimer's disease in Native Americans and whites. Int Psychogeriatr. 2003;15:367–375
- Effects of age, sex, and ethnicity in the association between apolipoprotein E genotype and Alzheimer's disease: a meta-analysis. JAMA. 1997;278:1349–1356
- Association between apolipoprotein E genotype and Alzheimer disease in African American subjects. Arch Neurol. 2002;59:594–600
- . Genetic and environmental epidemiology of Alzheimer's disease in Arabs residing in Israel. J Mol Neurosci. 2003;20:207–212
- The number of trait loci in late-onset Alzheimer disease. Am J Hum Genet. 2000;66:196–204
- . Cultural diversity in Alzheimer disease. Alzheimer Dis Assoc Disord. 2005;19:250–255
- APOE epsilon4 is not associated with Alzheimer's disease in elderly Nigerians. Ann Neurol. 2006;59:182–185
- The apolipoprotein E4 allele is not associated with an abnormal lipid profile in a Native American population following its traditional life style. Atherosclerosis. 1999;142:409–414
- . Clinical diagnosis and course of Azheimer's disease. Psychiatr Clin North Am. 1991;14:223–236
- . The neuropathology of Alzheimer disease in African American and white individuals. Arch Neurol. 2006;63:87–90
- . What we do and don't know about “race,” ethnicity, genetics, and health at the dawn of the genomic era. Nat Genet. 2004;36(Suppl. 11):S13–S16
- . On the impartial treatment of genetic and environmental hypotheses of racial differences. Am Psychologist. 2005;60:60–70
Supported in part by research grant AG 12300 from the National Institute on Aging, National Institutes of Health, Rockville, MD.
This perspective is offered by a clinician/researcher with 16 years of experience working in Oklahoma and Texas with American Indian dementia patients and their families. This work was made possible by funding from the National Institute on Aging of an American Indian Satellite awarded to the Alzheimer's Disease Center at the University of Texas Southwestern Medical Center, and by the cooperation of the Cherokee Nation, the Dallas Urban Intertribal Center, and the Choctaw Nation.
PII: S1552-5260(07)00635-8
doi: 10.1016/j.jalz.2007.10.016
© 2008 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 4, Issue 4
, Pages 233-238
, July 2008
