Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 4, Issue 4 , Pages 280-284 , July 2008

Comparison of costs of care between patients with Alzheimer's disease and dementia with Lewy bodies

  • Carolyn W. Zhu

      Affiliations

    • Geriatric Research, Education, and Clinical Center (GRECC) and Program of Research on Serious Physical and Mental Illness, Targeted Research Enhancement Program (TREP), James J. Peters VA Medical Center, Bronx, NY, USA
    • Brookdale Department of Geriatrics, Mount Sinai School of Medicine, New York, NY, USA
    • Corresponding Author InformationCorresponding author. Tel.: 718-584-9000, ext 3810; Fax: 718-741-4211.
    • ,
  • Nikolaos Scarmeas

      Affiliations

    • Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
    • Gertrude H. Sergievsky Center and the Department of Neurology, Columbia University Medical Center, New York, NY, USA
    • ,
  • Karina Stavitsky

      Affiliations

    • Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
    • Gertrude H. Sergievsky Center and the Department of Neurology, Columbia University Medical Center, New York, NY, USA
    • ,
  • Marilyn Albert

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
    • ,
  • Jason Brandt

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
    • ,
  • Deborah Blacker

      Affiliations

    • Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    • ,
  • Mary Sano

      Affiliations

    • Geriatric Research, Education, and Clinical Center (GRECC) and Program of Research on Serious Physical and Mental Illness, Targeted Research Enhancement Program (TREP), James J. Peters VA Medical Center, Bronx, NY, USA
    • Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    • ,
  • Yaakov Stern

      Affiliations

    • Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
    • Gertrude H. Sergievsky Center and the Department of Neurology, Columbia University Medical Center, New York, NY, USA

References 

  1. McKeith I, Mintzer J, Aarsland D, Burn D, Chiu H, Cohen-Mansfield J, et al. Dementia with Lewy bodies. Lancet Neurol. 2004;3:19–28
  2. Murman DL, Kuo SB, Powell MC, Colenda CC. The impact of parkinsonism on costs of care in patients with AD and dementia with Lewy bodies. Neurology. 2003;61:944–949
  3. Bostrom F, Jonsson L, Minthon L, Londos E. Patients with Lewy body dementia use more resources than those with Alzheimer's disease. Int J Geriatr Psychiatry. 2007;22:713–719
  4. Stern Y, Folstein M, Albert M, Richards M, Miller L, Bylsma F, et al. Multicenter study of predictors of disease course in Alzheimer disease (the “predictors study”): I0151study design, cohort description, and intersite comparisons. Alzheimer Dis Assoc Disord. 1993;7:3–21
  5. Richards M, Folstein M, Albert M, Miller L, Bylsma F, Lafleche G, et al. Multicenter study of predictors of disease course in Alzheimer disease (the “predictors study”): II—neurological, psychiatric, and demographic influences on baseline measures of disease severity. Alzheimer Dis Assoc Disord. 1993;7:22–32
  6. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939–944
  7. McKeith IG, Galasko D, Kosaka K, Perry EK, Dickson DW, Hansen LA, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology. 1996;47:1113–1124
  8. Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189–198
  9. Stern Y, M S, Paulson J, Mayeux R. Modified mini-mental state examination: validity and reliability. Neurology. 1987;37(Suppl 1):179
  10. Zhu CW, Scarmeas N, Torgan R, Albert M, Brandt J, Blacker D, et al. Longitudinal study of effects of patient characteristics on direct costs in Alzheimer disease. Neurology. 2006;67:998–1005
  11. Zhu CW, Scarmeas N, Torgan R, Albert M, Brandt J, Blacker D, et al. Clinical features associated with costs in early AD: baseline data from the Predictors Study. Neurology. 2006;66:1021–1028
  12. Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry. 1968;114:797–811
  13. Devanand DP, Miller L, Richards M, Marder K, Bell K, Mayeux R, et al. The Columbia University Scale for Psychopathology in Alzheimer's disease. Arch Neurol. 1992;49:371–376
  14. Stern Y, Tang MX, Albert MS, Brandt J, Jacobs DM, Bell K, et al. Predicting time to nursing home care and death in individuals with Alzheimer disease. JAMA. 1997;277:806–812
  15. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–383
  16. Scarmeas N, Brandt J, Albert M, Hadjigeorgiou G, Papadimitriou A, Dubois B, et al. Delusions and hallucinations are associated with worse outcome in Alzheimer disease. Arch Neurol. 2005;62:1601–1608
  17. Council of Economic Advisers. Economic report of the President. 2003;Washington, DC
  18. Neyman JS. On the application of probability theory to agriculture experiments: essay on principles—section 9. Statistical Science. 1990;5:465–485
  19. Abadie A, Drukker D, Herr J, Imbens G. Implementing matching estimators for average treatment effects in Stata. The Stata Journal. 2004;4:290–311
  20. Husaini BA, Sherkat DE, Levine R, Bragg R, Holzer C, Anderson K, et al. Race, gender, and health care service utilization and costs among Medicare elderly with psychiatric diagnoses. J Aging Health. 2002;14:79–95
  21. Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. Br J Psychiatry. 1982;140:566–572

PII: S1552-5260(08)00080-0

doi: 10.1016/j.jalz.2008.02.008

Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 4, Issue 4 , Pages 280-284 , July 2008

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