Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 5, Issue 1 , Pages 50-60 , January 2009

Immediate and delayed effects of cognitive interventions in healthy elderly: A review of current literature and future directions

  • Kathryn V. Papp

      Affiliations

    • Department of Psychology, University of Connecticut, Storrs, CT, USA
    • ,
  • Stephen J. Walsh

      Affiliations

    • Center for Biostatistics, University of Connecticut School of Medicine, Farmington, CT, USA
    • ,
  • Peter J. Snyder

      Affiliations

    • Lifespan Affiliated Hospitals and the Department of Clinical Neurosciences, The Warren Alpert Medical School, Brown University, Providence, RI, USA
    • Corresponding Author InformationCorresponding author. Tel.: 401-444-5113; Fax: 401-444-6895.

References 

  1. Thal LJ, Carta A, Doody R, Leber P, Mohs R, Schneider F, et al. Prevention protocols for Alzheimer disease: position paper from the international working group on harmonization of dementia drug guidelines. Alzheimer Dis Assoc Disord. 1997;11(Suppl 3):46–49
  2. Belleville S. MCI Conference paper: cognitive training for persons with mild cognitive impairment. Int Psychogeriatr. 2007;25:1–10
  3. Sitzer DI, Twamley EW, Jeste DV. Cognitive training in Alzheimer's disease: a meta-analysis of the literature. Acta Psychiatr Scand. 2006;114:75–90
  4. Ball LJ, Birge SJ. Prevention of brain aging and dementia. Clin Geriatr Med. 2002;18:485–503
  5. Settersten RA. Lives in time and place. Amityville, NY: Baywood; 1999;
  6. Lazarov O, Robinson J, Tang YP, Hairston HS, Korade-Mirnics Z, Lee VMY, et al. Environmental enrichment reduces Aβ levels and amyloid deposition in transgenic mice. Cell. 2005;120:701–713
  7. Berardi N, Braschi C, Capsoni S, Cattaneo A, Maffei L. Environmental enrichment delays the onset of memory deficits and reduces neuropathological hallmarks in a mouse model of Alzheimer-like neurodegeneration. J Alzheimers Dis. 2007;11:359–370
  8. Boyles JK, Zoellner CD, Anerson JL, Kosik LM, Pitas RE, Wesigraber KH. A role for apolipoprotein E, apolioptotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. J Clin Invest. 1989;83:1015–1031
  9. Wilson RS, Barnes LL, Bennett DA. Assessment of lifetime participation in cognitively stimulating activities. J Clin Exp Neuropsychol. 2003;25:634–642
  10. Wilson RS, Bennett DA, Bienias JL, Aggarwal NT, Mendes de Leon CF, Morris MC, et al. Cognitive activity and incident AD in a population-based sample of older persons. Neurology. 2002;59:1910–1914
  11. Wilson RS, Bennett DA, Bienias JL, Mendes de Leon CL, Morris MC, Evans DA. Cognitive activity and cognitive decline in a biracial community population. Neurology. 2003;61:812–816
  12. Verghese J, Lipton R, Katz M, Hall C, Derby C, Kuslansky G. Leisure activities and the risk of dementia in the elderly. N Engl J Med. 2003;348:2508–2516
  13. Fratiglioni L, Paillard-Borg S, Winbald B. An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurol. 2004;3:343–353
  14. Briones TL. Environment, physical activity, and neurogenesis: implications for prevention and treatment of Alzheimer's disease. Curr Alzheimer Res. 2006;3:49–54
  15. Scarmeas N, Levy G, Tang MX, Manly J, Stern Y. Influence of leisure activity on the incidence of Alzheimer's disease. Neurology. 2001;57:2236–2242
  16. Ott A, Van Rossum CTM, Van Harskamp F, Van de Mheen H, Hofman A, Breteler MMB. Education and the incidence of dementia in a large population-based study: the Rotterdam study. Neurology. 1999;52:663
  17. Stern Y. Cognitive reserve and Alzheimer's disease. Alzheimer Dis Assoc Disord. 2006;20:112–117
  18. Verhaeghen P, Marcoen A, Goossens L. Improving memory performance in the aged through mnemonic training: a meta-analytic study. Psychol Aging. 1992;7:242–251
  19. McAuliffe K. Mental fitness. Discover Magazine, September 2008:56–60.
  20. Aamdot S, Wang S. Exercise on the brain. New York Times, November 8, 2007:Opinion.
  21. Baker B. Is it really smart to teach old brains new tricks? Washington Post, August 9, 2008:HE01.
  22. Fuyuno I. Brain craze. Nature. 2007;447:18–20
  23. Raschetti R, Albanese E, Vanacore N, Maggini M. Cholinesterase inhibitors in MCI: a systematic review of randomised trials. PLoS Med. 2007;4:e338
  24. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials. 1996;7:1–12
  25. Petiti DM. Meta analysis, decision analysis and cost effectiveness analysis. 2nd ed.. Oxford, UK: Oxford University Press; 2000;
  26. Trowman R, Dumwille JC, Torgerson DJ, Cranny G. The impact of trial baseline imbalances should be considered in systematic reviews: a methodological case study. J Clin Epidemiol. 2007;60:1229–1233
  27. Bugos JA, Perlstein WM, McCrae CS, Brophy TS, Bedenbaugh PH. Individualized piano instruction enhances executive functioning and working memory in older adults. Aging Ment Health. 2007;11:464–471
  28. Edwards JD, Wadley VG, Myers RS, Roenker DL, Cissell GM, Ball KK. Transfer of a speed of processing intervention to near and far cognitive functions. Gerontology. 2002;48:329–340
  29. Fabre C, Chamari K, Mucci P, Masse-Biron J, Prefaut C. Improvement of cognitive function by mental and/or individualized aerobic training in healthy elderly subjects. Int J Sports Med. 2002;23:415–421
  30. Mahncke HW, Connor B, Appelman J, Ahsanuddin ON, Hardy JL, Wood RA, et al. Memory enhancement in healthy older adults using a brain plasticity-based training program: a randomized, controlled study. Proc Natl Acad Sci U S A. 2006;103:12523–12528
  31. Margrett JA, Willis SL. In-home cognitive training with older married couples: individual versus collaborative learning. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2006;13:173–195
  32. Oswald WD, Rupprecht R, Gunzelmann T, Tritt K. The SIMA-project: effects of 1 year cognitive and psychomotor training on cognitive abilities of the elderly. Behav Brain Res. 1996;78:67–72
  33. Willis SL, Tennstedt SL, Marsike M, Ball K, Elias J, Koepke KM, et al. Long-term effects of cognitive training on everyday functional outcomes in older adults. JAMA. 2006;296:2805
  34. Buiza C, Etxeberria I, Galdona N, Gonzalez MF, Arriola E, Lopez de Munain A, et al. A randomized, two-year study of the efficacy of cognitive intervention on elderly people: the Donostia Longitudinal Study. Int J Geriatr Psychiatry. 2008;23:85–94
  35. Zelinski EM, Yaffe K, Ruff RM, Kennison RK, Smith GE. The IMPACT Study: a randomized controlled trial of a brain plasticity-based training program for age-related cognitive decline. Presented at The Gerontological Society of America, November 16–20, 2007, San Francisco, CA.
  36. Rasmunsson DX, Rebok GW, Bylsma FW, Brant J. Effects of three types of memory training in normal elderly. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 1999;6:56–66
  37. Pietrzak RH, Mollica CM, Maruff P, Snyder PJ. Cognitive effects of immediate-release methylphenidate in children with attention-deficit/hyperactivity disorder. Neurosci Biobehav Rev. 2006;30:1225–1245
  38. West RL, Yassuda MS. Aging and memory control beliefs: performance in relation to goal setting and memory self-evaluation. J Gerontol Psychol Sci Soc Sci. 2004;59:56–65
  39. Valenzuela MJ, Jones M, Wen W, Rae C, Graham S, Shnier R, et al. Memory training alters hippocampal neurochemistry in health elderly. Aging. 2003;14:1333–1337
  40. Seshadri S, Besier A, Selhub J, Jacques PF, Rosenberg IH, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med. 2002;346:476–483
  41. Heyn P, Abreu BC, Ottenbacher KJ. The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch Phys Med Rehabil. 2004;85:1694–1704
  42. Selwood A, Thorgrimsen L, Orrell M. Quality of life in dementia: a one-year follow-up study. Int J Geriatr Psychiatry. 2005;20:232–237
  43. Belleville S, Gilbert B, Fontaine F, Gagnon L, Menard E, Gauthier S. Improvement of episodic memory in persons with mild cognitive impairment and healthy older adults: evidence from a cognitive intervention program. Dement Geriatr Cogn Disord. 2006;22:486–499
  44. Jaeggi SM, Buschkuehl M, Jonides J, Perrig WJ. Improving fluid intelligence with training on working memory. Proc Natl Acad Sci U S A. 2008;105:6829–6833
  45. Calero MD, Navarro E. Cognitive plasticity as a modulating variable on the effects of memory training in elderly persons. Arch Clin Neuropsychol. 2007;22:63–72
  46. Bond GE, Wolf-Wilets V, Fiedler FE, Burr RL. Computer-aided cognitive training of the aged: a pilot study. Clin Gerontol. 2002;22:19
  47. Ghyme SW, Kim MY, Choi JS. Cognitive training with virtual reality. Proc Intern Conf Imaging Sci. Systems Technol. 2003;1:358–364

PII: S1552-5260(08)02922-1

doi: 10.1016/j.jalz.2008.10.008

Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 5, Issue 1 , Pages 50-60 , January 2009

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