Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 6, Issue 1 , Pages 63-69 , January 2010

Subtypes of depression among patients with Alzheimer's disease and other dementias

This study was presented in part as a poster at the XXVI Congress of the Collegium Internationale Neuropsychopharmacologicum (CINP), Munich, Germany, on July 13–17 2008.

  • Ruby C. Castilla-Puentes

      Affiliations

    • Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA, and Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA
    • Corresponding Author InformationCorresponding author. Tel.: 610–864–2528; Fax: 215–546–1432.
    • ,
  • Miguel E. Habeych

      Affiliations

    • Department of Neurological Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA

References 

  1. Burns A. Affective symptoms in Alzheimer's disease. Int J Geriatr Psychiatry. 1991;6:371–376
  2. Ballard CG, Bannister C, Oyebode F. A review—depression in dementia sufferers. Int J Geriatr Psychiatry. 1996;11:507–515
  3. Verhay FRJ, Rozendaal N, Ponds WHM, Jolks J. Dementia awareness and depression. Int J Geriatr Psychiatry. 1993;8:851–856
  4. Greenwald BS, Kramer-Ginsberg E, Marin DB, Laitman LB, Hermann CK, Mohs RC. Dementia with co-existent major depression. Am J Psychiatry. 1989;146:1472–1478
  5. Sultzer DL, Levin HS, Mahler ME, High WM, Cummings JL. A comparison of psychiatric symptoms in vascular dementia and Alzheimer's disease. Am J Psychiatry. 1993;150:1806–1812
  6. Cummings JL, Miller B, Hill MA, Neshkes R. Neuropsychiatric aspects of multi-infarct dementia and dementia of the Alzheimer type. Arch Neurol. 1987;44:389–393
  7. Greenwald BS, Kramer-Ginsberg E, Marin DB, Laitman LB, Hermann CK, Mohs RC, et al. Dementia with coexistent major depression. Am J Psychiatry. 1989;146:1472–1478
  8. Motheral BR, Fairman KA. The use of claims databases for outcomes research: rationale, challenges, and strategies. Clin Ther. 1997;19:346–366
  9. Gomez-Caminero A, Blumentals WA, Russo LJ, Brown R, Castilla-Puentes R. Does panic disorder increase the risk of coronary heart disease? A cohort study of a national managed care database. Psychosom Med. 2005;67:688–691
  10. Blumentals WA, Gomez-Caminero A, Joo S, Vannappagari V. Should erectile dysfunction be considered as a marker for acute myocardial infarction? Results from a retrospective cohort study. Int J Impot Res. 2004;16:350–353
  11. Shea A, Curtis L, Szczech L, Schulman K. Sensitivity of International Classification of Diseases codes for hyponatremia among commercially insured outpatients in the United States. BMC Nephrol. 2008;9:5
  12. Whitley R, Davis E, Suppapanya N. Incidence of neonatal herpes simplex virus infections in a managed-care population. Sex Transm Dis. 2007;34:704–708
  13. Kessler RC, Cantrell CR, Berglund P, Sokol MC. The effects of copayments on medication adherence during the first two years of prescription drug treatment. J Occup Environ Med. 2007;49:597–609
  14. Issa M, Fenter T, Black L, Grogg A, Kruep E. An assessment of the diagnosed prevalence of diseases in men 50 years of age or older. Am J Manag Care. 2006;12(Suppl):S83–S89
  15. Boland RJ. Depression in Alzheimer's disease and other dementias. Curr Psychiatry Rep. 2000;2:427–433
  16. Payne JL, Lyketsos CG, Steele C, Baker L, Galik E, Kopunek S, et al. Relationship of cognitive and functional impairment to depressive features in Alzheimer's disease and other dementias. Neuropsychiatry Clin Neurosci. 1998;10:440–447
  17. Branconnierm RJ, Cole JO, Ghazvinian D, Spera KF, Oxenkrug GF, Bass JL. Clinical pharmacology of bupropion and imipramine in elderly depressives. J Clin Psychiatry. 1983;44:130–133
  18. Beekman AT, Copeland JR, Prince MJ. Review of community prevalence of depression in later life. Br J Psychiatry. 1999;174:307–311
  19. Brodaty H, Draper B, Saab D, Low LF, Richards V, Paton H, et al. Psychosis, depression and behavioural disturbances in Sydney nursing home residents: prevalence and predictors. Int J Geriatr Psychol. 2001;16:504–512
  20. Nygaard HA, Ruths S. Missing the diagnosis: senile dementia in patients admitted to nursing homes. Scand J Prim Health Care. 2003;21:148–152
  21. Cooper JK, Mungas D. Risk factor and behavioural differences between vascular and Alzheimer's dementias: the pathway to end-stage disease. J Geriatr Psychiatry Neurol. 1993;6:29–33
  22. Reichman WE, Coyne AC. Depressive symptoms in Alzheimer's disease and multi-infarct dementia. J Geriatr Psychiatry Neurol. 1995;8:96–99
  23. Fischer P, Simanyi M, Danielczyk W. Depression in dementia of the Alzheimer type and in multi-infarct dementia. Am J Psychiatry. 1990;147:1484–1487
  24. Landes AM, Sperry SD, Strauss ME. Prevalence of apathy, dysphoria, and depression in relation to dementia severity in Alzheimer's disease. J Neuropsychol Clin Neurosci. 2005;17:342–349
  25. Forsell Y, Winblad B. Major depression in a population of demented and nondemented older people: prevalence and correlates. J Am Geriatr Soc. 1998;46:27–30
  26. Starkstein SE, Jorge R, Mizrahi R, Robinson RG. The construct of minor and major depression in Alzheimer's disease. Am J Psychiatry. 2005;162:2086–2093
  27. Lyketsos CG, Steinberg M, Tschanz JT, Norton MC, Steffens DC, Breitner JC. Mental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in Aging. Am J Psychiatry. 2000;157:708–714
  28. Cummings JL, Ross W, Absher J, Gornbein J, Hadjiaghai L. Depressive symptoms in Alzheimer disease: assessment and determinants. Alzheimer Dis Assoc Disord. 1995;9:87–93
  29. Vilalta-Franch J, Garre-Olmo J, Lopez-Pousa S, Turon-Estrada A, Lozano-Gallego M, Hernandez-Ferrandiz M, et al. Missing the diagnosis: senile dementia in patients admitted to nursing homes. Scand J Prim Health Care. 2003;21:148–152
  30. Olin J, Schneider LS, Katz IR, Meyers BS, Alexopoulos GS, Breigtner JC, et al. Provisional diagnostic criteria for depression of Alzheimer's disease. Am J Geriatr Psychiatry. 2002;10:125–128
  31. Burns A, Jacoby R, Levy R. Psychiatric phenomena in Alzheimer's disease—III: disorders of mood. Br J Psychiatry. 1990;157:81–86
  32. Merriam A, Aronson N, Gaston P, et al. The psychiatric symptoms of Alzheimer's disease. J Am Geriatr Soc. 1988;36:7–12
  33. Lyness JM, Conwell Y, Nelson JC. Suicide attempts in elderly psychiatric inpatients. J Am Geriatr Soc. 1992;40:320–324
  34. Musetti L, Perugi G, Soriani A, Rossi VM, Cassano GB. Depression before and after age 65: a re-examination. Br J Psychiatry. 1989;155:330–336
  35. Lyketsos CG, Steele C, Baker L, Galik E, Kopunek S, Steinberg M, et al. Major and minor depression in Alzheimer's disease: prevalence and impact. J Neuropsychiatry Clin Neurosci. 1997;9:556–561
  36. Migliorelli R, Teson A, Sabe L, Petracchi M, Leiguarda R, Starkstein SE. Prevalence and correlates of dysthymia and major depression among patients with Alzheimer's disease. Am J Psychiatry. 1995;152:37–44
  37. Sultzer DL, Levin HS, Mahler ME, High WM, Cummings JL. A comparison of psychiatric symptoms in vascular dementia and Alzheimer's disease. Am J Psychiatry. 1993;150:1806–1812
  38. Ballard C, Bannister C, Solis M, Oyebode F, Wilcock G. The prevalence, associations, and symptoms of depression amongst dementia sufferers. J Affect Disord. 1996;36:135–144
  39. Groves WC, Brant J, Steinberg M, Warren A, Rosemblatt A, Baker A, et al. Vascular dementia and Alzheimer's disease: is there a difference?: a comparison of symptoms by disease duration. J Neuropsychiatry Clin Neurosci. 2000;12:305–315
  40. Newman S. The prevalence of depression in Alzheimer's disease and vascular dementia in a population sample. J Affect Disord. 1999;52:169–176
  41. Berrios CE, Bakshi N. Manic and depressive symptoms in the elderly: their relationships to treatment outcome, cognition, and motor symptoms. Psychopathology. 1991;24:31–38
  42. Vilalta-Franch J, Lopez-Pousa S, Llinas-Regla J. Prevalence of depressive disorders in dementia. Rev Neurol. 1998;26:57–60
  43. Ballard C, Neill D, O'Brien J, McKeith IG, Ince P, Perry R. Anxiety, depression and psychosis in vascular dementia: prevalence and associations. J Affect Disord. 2000;59:97–106
  44. Steinberg M, Shao H, Zandi P, Lyketsos CG, Welsh-Bohmer KA, Norton MC, et al. Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry. 2008;23:170–177

 Dr. Castilla-Puentes is currently Director, Post-Marketing Safety Expert with Johnson & Johnson, Pharmaceutical Research and Development.

PII: S1552-5260(09)00107-1

doi: 10.1016/j.jalz.2009.04.1232

Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 6, Issue 1 , Pages 63-69 , January 2010

Article Tools

* Image Usage & Resolution