Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 6, Issue 1 , Pages 1-10.e1, January 2010

Efficacy of a medical food in mild Alzheimer's disease: A randomized, controlled trial

  • Philip Scheltens

      Affiliations

    • Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: 31-20-444-0742; Fax: 31-20-444-0715.
  • ,
  • Patrick J.G.H. Kamphuis

      Affiliations

    • Danone Research, Centre for Specialised Nutrition, Wageningen, The Netherlands
  • ,
  • Frans R.J. Verhey

      Affiliations

    • Alzheimer Centre Limburg, Maastricht University Medical Centre, The Netherlands
  • ,
  • Marcel G.M. Olde Rikkert

      Affiliations

    • Alzheimer Centre Nijmegen, Radboud University Medical Centre Nijmegen, The Netherlands
  • ,
  • Richard J. Wurtman

      Affiliations

    • Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA
  • ,
  • David Wilkinson

      Affiliations

    • Memory Assessment and Research Centre, Moorgreen Hospital, Southampton, United Kingdom
  • ,
  • Jos W.R. Twisk

      Affiliations

    • Department of Health Sciences, VU University Medical Center, Amsterdam, The Netherlands
  • ,
  • Alexander Kurz

      Affiliations

    • Department of Psychiatry, Klinikum Rechts der Isar, Technische Universität München, Germany

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 Potential conflicts of interest: P. Scheltens is employed by VU University Medical Center, Amsterdam. The Alzheimer Center VU University Medical Center receives unrestricted funding from Danone Research. He is a member of the Nutricia Advisory Board; P.J.G.H. Kamphuis is an employee of Danone Research; F.R.J. Verhey is employed by the Department of Psychiatry and Neuropsychology of the Maastricht University Medical Centre. He is a member of the Nutricia Advisory Board; M.G.M. Olde Rikkert is employed by the Geriatric Department of the Radboud University Medical Centre Nijmegen. He is a member of the Nutricia Advisory Board; R.J. Wurtman is employed by The Massachusetts Institute of Technology, which owns patents on uridine, omega-3 fatty acids, and choline to treat brain diseases by enhancing synapses. He is consultant to the Danone Company and advises on research related to such uses; D. Wilkinson has no conflicts of interest to declare; J.W.R. Twisk has no conflicts of interest to declare; A. Kurz has no conflicts of interest to declare.

 Contributors: Investigators: P. Scheltens, M.G.M. Olde Rikkert, F. Verhey, P. Dautzenberg, R.J. van Marum, L. Boelaarts, J.P.J. Slaets, D.C.M. Verheijen, S. Stevens, A. Weverling, E. Sanders, A. Kurz, H. Gertz, V. Holthoff, J. Schröder, H. Jahn, R. Horn, M. Ribbat, G. Reifschneider, K. Oehler, R. Schellenberg, K. Steinwachs, R. Vandenberghe, P.P. de Deyn, N. de Klippel, M. Petrovic, Ph. Bourgeois, Ph. PPMGA Tack, D. Wilkinson, T.K. Malstrom; Steering committee: M.J. van der Mooren (Chairman), P. Scheltens, P.J.G.H. Kamphuis; Independent data monitoring committee: I.G. McKeith, K. Rockwood, J.H. Koeman, J.W.R. Twisk.

PII: S1552-5260(09)02329-2

doi:10.1016/j.jalz.2009.10.003

Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 6, Issue 1 , Pages 1-10.e1, January 2010