Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 6, Issue 5 , Pages 378-385, September 2010

Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss

  • Michelle M. Mielke

      Affiliations

    • Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • Corresponding Author InformationCorresponding author: Tel.: 443-326-5174; Fax: 410-550-1407.
    • ,
  • Norman J. Haughey

      Affiliations

    • Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • ,
  • Veera Venkata Ratnam Bandaru

      Affiliations

    • Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • ,
  • Steven Schech

      Affiliations

    • Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • ,
  • Richard Carrick

      Affiliations

    • Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • ,
  • Michelle C. Carlson

      Affiliations

    • Center on Aging and Health, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    • ,
  • Susumu Mori

      Affiliations

    • Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • F.M. Kirby Center on Brain Imaging at the Kennedy Kreiger Institute, Johns Hopkins University, Baltimore, MD, USA
    • ,
  • Michael I. Miller

      Affiliations

    • Center for Imaging Science, The Johns Hopkins University, Baltimore, MD, USA
    • ,
  • Can Ceritoglu

      Affiliations

    • Center for Imaging Science, The Johns Hopkins University, Baltimore, MD, USA
    • ,
  • Timothy Brown

      Affiliations

    • Center for Imaging Science, The Johns Hopkins University, Baltimore, MD, USA
    • ,
  • Marilyn Albert

      Affiliations

    • Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • ,
  • Constantine G. Lyketsos

      Affiliations

    • Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 30.00 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

 While funding for the neuroimaging and participant follow-up was partially obtained through a grant from GlaxoSmithKline, the authors had access to the data at all times and retain the data. Funding for the plasma lipids were obtained from National Institutes of Health grants. All authors report no conflicts of interests with regards to GlaxoSmithKline or any other organization. All participants provided informed consent and the study was approved by the Johns Hopkins University Institutional Review Board.

PII: S1552-5260(10)00099-3

doi:10.1016/j.jalz.2010.03.014

Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume 6, Issue 5 , Pages 378-385, September 2010

Article Tools

* Image Usage & Resolution