| Editorial |
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Research in context
The role of multidisciplinary medical journals such as Alzheimer's & Dementia is to communicate research findings to a broad audience interested in a diverse array of scientific topics. The discus...
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Ara S. Khachaturian
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171
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| Featured Articles |
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An investigation of PreMCI: Subtypes and longitudinal outcomes
Abstract: Background/Aims: To investigate the clinical features and rates of progression of conditions that are not considered to be normal, but do not fulfill criteria for mild cognitive impairment (...
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David A. Loewenstein,
Maria T. Greig,
John A. Schinka,
Warren Barker,
Qian Shen,
Elizabeth Potter,
Ashok Raj,
Larry Brooks,
Daniel Varon,
Michael Schoenberg,
Jessica Banko,
Huntington Potter,
Ranjan Duara
et al.
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172-179
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Effects of Food and Drug Administration-approved medications for Alzheimer’s disease on clinical progression
03 February 2012
Abstract: Background: Observational studies suggest that cholinesterase inhibitors and/or memantine may delay clinical progression of Alzheimer’s disease (AD) in 40% of individuals taking the medicati...
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Michelle M. Mielke,
Jeannie-Marie Leoutsakos,
Chris D. Corcoran,
Robert C. Green,
Maria C. Norton,
Kathleen A. Welsh-Bohmer,
JoAnn T. Tschanz,
Constantine G. Lyketsos
et al.
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180-187
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Diuretic use is associated with better learning and memory in older adults in the Ginkgo Evaluation of Memory study
05 April 2012
Abstract: Background: To investigate the association between diuretics, angiotensin-converting enzyme inhibitors (ACE-I), angiotensin II receptor blockers (AT2RB), and cognitive function. Methods: Thi...
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Sevil Yasar,
Fu-Mei Lin,
Linda P. Fried,
Claudia H. Kawas,
Kaycee M. Sink,
Steven T. DeKosky,
Michelle C. Carlson,
Ginkgo Evaluation of Memory (GEM) Study Investigators
et al.
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188-195
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Serum antibodies to periodontal pathogens are a risk factor for Alzheimer’s disease
Abstract: Background: Chronic inflammation in periodontal disease has been suggested as a potential risk factor in Alzheimer’s disease (AD). The purpose of this study was to examine serum antibody lev...
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Pamela Sparks Stein,
Michelle J. Steffen,
Charles Smith,
Gregory Jicha,
Jeffrey L. Ebersole,
Erin Abner,
Dolph Dawson
et al.
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196-203
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Medical and environmental risk factors associated with frontotemporal dementia: A case-control study in a veteran population
05 April 2012
Abstract: Background: Compared with other major dementias, very little is known about the medical and environmental risk factors associated with frontotemporal dementia (FTD). In this study, we evalua...
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Yogeshwar V. Kalkonde,
Ali Jawaid,
Salah U. Qureshi,
Peyman Shirani,
Michael Wheaton,
Gineth P. Pinto-Patarroyo,
Paul E. Schulz
et al.
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204-210
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Cognitive and structural magnetic resonance imaging features of Lewy body dementia and Alzheimer’s disease
Abstract: Objective: To assess medial temporal atrophy (MTA) and atrophy adjacent to the third ventricle (Peri-IIIVent) on brain magnetic resonance images as biomarkers for the diagnosis of Alzheimer’...
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Miriam Jocelyn Rodriguez,
Elizabeth Potter,
Qian Shen,
Warren Barker,
Maria Greig-Custo,
Joscelyn Agron,
David Loewenstein,
Ranjan Duara
et al.
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211-218
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Nonsteroidal anti-inflammatory drug use and the risk of cognitive impairment and Alzheimer’s disease
Abstract: Background: Some observational studies have established an association between exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) and a decreased risk of subsequently developing Alzhe...
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Sharlène Côté,
Pierre-Hugues Carmichael,
René Verreault,
Joan Lindsay,
Jean Lefebvre,
Danielle Laurin
et al.
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219-226
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| Perspectives |
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Alzheimer’s disease: Pathogenesis and prevention
05 April 2012
Abstract: Tau lesions (pretangles, neuropil threads, neurofibrillary tangles) in select neuronal types are essential to the pathogenesis of Alzheimer’s disease. Pretangle formation marks the beginning...
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Heiko Braak,
Kelly Del Tredici
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227-233
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The draft “National Plan” to address Alzheimer's disease - National Alzheimer's Project Act (NAPA)
Abstract: This perspective updates the status of the “National Plan to Address Alzheimer's Disease” and the recommendations of the NAPA Advisory Council's Sub-committee on Research. Here, we identify ...
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Zaven S. Khachaturian,
Ara S. Khachaturian,
William Thies
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234-236
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| Meeting Report |
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The epidemiology of Alzheimer’s disease: Laying the foundation for drug design, conduct, and analysis of clinical trials
Abstract: Epidemiological studies increasingly inform Alzheimer’s disease (AD) public health impact, prevention strategies, drug targets, therapeutic interventions, and clinical trial design. For this...
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Kristine Yaffe,
Michael Tocco,
Ronald C. Petersen,
Catherine Sigler,
Leah C. Burns,
Christel Cornelius,
Ara S. Khachaturian,
Michael C. Irizarry,
Maria C. Carrillo
et al.
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237-242
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| Association Pages |
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Alzheimer's Association Update for May 2012
When the National Institute on Aging holds its Alzheimer's Disease Research Summit this month, it will be informed by a scientific agenda prepared by some of the nation's leading Alzheimer's disease (...
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243-245
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| Frontmatter |
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Contents
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A1-A2
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Editorial Board
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A3
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Medical and Scientific Advisory Council
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A4
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Subscriber information
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A5
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